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Tridopa 50mg+12.5mg +200mg Tablet | 1 Strip
Prescribed for the management of Parkinson’s disease and treatment of “end-of-dose” motor fluctuations.
Pregnancy: Category C – use only if clearly needed.
Lactation: Unknown if excreted in breast milk; use cautiously.
Elderly: Increased susceptibility to adverse effects; dose adjustments may be necessary.
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ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Tridopa 50 combines Levodopa, Carbidopa, and Entacapone for synergistic action:
- Levodopa – A dopamine precursor that crosses the blood-brain barrier and is converted to dopamine, helping restore motor control.
- Carbidopa – A peripheral decarboxylase inhibitor that prevents the breakdown of Levodopa before it reaches the brain, enhancing its effectiveness.
- Entacapone – A selective COMT inhibitor that prolongs the effect of Levodopa by maintaining higher and sustained plasma levels, providing better control of Parkinson’s symptoms.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Side Effects | Tridopa 50
Very Common (>10%)
Dyskinesia, nausea, diarrhea, hyperkinesia, urine discoloration.
Common (1–10%)
Dizziness, fatigue, anxiety, insomnia, hallucinations, abdominal pain, constipation, vomiting, dry mouth, increased sweating.
Other Possible Effects
Abnormal dreams, orthostatic hypotension, headache, abnormal voluntary movements, agitation, back pain, dyspnea, blurred vision.
Potentially fatal: Rare cases of rhabdomyolysis reported.
✔️ Dosage & Administration |Tridopa 50
Adult: Oral – Initial dose: 1 tablet daily. Dose should be titrated based on patient response.
Recommended: 1 tablet per administration, maximum 8 tablets/day.
Severe hepatic impairment: Contraindicated.
Pediatric use: Safety and efficacy not established.
Tablets must be swallowed whole, not crushed or chewed.
Can be taken with or without food, but avoid high-protein meals and iron supplements, which reduce absorption.
✔️ Drug Interactions | Tridopa 50
Increased risk of severe postural hypotension with antihypertensives or MAO inhibitors.
Iron salts, phenytoin, and papaverine reduce efficacy of Levodopa.
Dopamine antagonists (e.g., certain antipsychotics) may reduce benefit.
Drugs affecting biliary excretion may raise entacapone levels.
May influence hormonal secretion (decrease prolactin, increase growth hormone).
✔️ Contraindications:
Hypersensitivity to any of the ingredients.
Narrow-angle glaucoma.
History or suspicion of melanoma or undiagnosed skin lesions.
Severe liver dysfunction.
✔️ Precautions & Warnings
- Monitor liver, kidney, hematopoietic, and cardiovascular function during long-term therapy.
- Use with caution in patients with chronic wide-angle glaucoma or biliary obstruction.
- Sudden discontinuation may cause severe withdrawal symptoms (fever, rigidity, confusion).
- Caution advised in pregnancy and lactation (Category C).
- May cause daytime sleepiness, dizziness, and hallucinations; patients should avoid driving until they know how the drug affects them.
✔️ Storage:
Store in a cool, dry place below 30°C.
Protect from light and moisture.
Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
